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HOPO chelator

Gadolinium Poisoning, Gadolinium Toxicity

Fine Chemicals

Gadolinium Poisoning, Gadolinium Toxicity Most of the known toxicity of the free Gd3+ ion is related to 2 properties: its insolubility at physiologic pH, resulting in very slow systemic excretion; and an ionic radius close to that of Ca2+ (…

Gadolinium side effects

Fine Chemicals

Gadolinium side effects GBCAs and MRIs Gadolinium-based contrast agents (GBCAs) are soluble metal-ligand complexes of gadolinium ion Gd3+. Contrast agents fall into the definition of drugs as a tool for making a medical diagnosis [1]. GBCAs…

Ultimate Chelator HOPO for Zirconium-89 (89Zr) based PET imaging agents

Fine Chemicals

Ultimate Chelator HOPO for Zirconium-89 (89Zr) based PET imaging agents Zirconium-89 is an effective radionuclide for antibody-based positron emission tomography (PET) imaging because its physical half-life (78.41 h) matches the biological …

Detox gadolinium from my body? – HOPO chelator

Fine Chemicals

How should I detox gadolinium from my body? We have found that chelation therapy and the use of specific oral supplements is the best treatment for most patients. Chelation is especially valuable – a procedure which uses a specific binding …